The following statement is not true of ‘potency’ of a drug:
A receptor which itself has enzymatic property is:
All of the following subserve as intracellular second messengers in receptor mediated signal transduction except:
The following receptor has an intrinsic ion channel:
The elderly patients are relatively intolerant to:
The following statement is true in relation to ‘drug toxicity’ and ‘poisoning’:
A drug which does not produce any action by itself but decreases the slope of the log dose-response curve and suppresses the maximal response to another drug is a:
An undesirable effect of a drug that occurs at thera peutic doses and can be predicted from its pharma cological actions is called:
In congestive heart failure patients:
Fixed dose combination formulations are not necessarily appropriate for:
If the dose-response curves of a drug for producing different actions are widely separated on the dose axis, the drug is:
Select the receptor that is located intracellularly:
Which racial difference in response to drugs has been mentioned incorrectly below:
The receptor transduction mechanism with the fastest time-course of response effectuation is:
Which of the following is true of ‘placebos’:
Interindividual variations in equieffective doses of a drug are most marked if it is disposed by:
In patients of hepatic cirrhosis:
Agonists affect the receptor molecule in the following manner:
The antagonism between adrenaline and histamine is called ‘physiological antagonism’ because:
The following is not a feature of competitive antagonists:
Agonist induced autophosphorylation, internalization and down regulation is a distinctive feature of:
‘Drug efficacy’ refers to:
Higher efficacy of a drug necessarily confers:
The antidotal action of sodium nitrite in cyanide poison ing is based on:
Which of the following drugs exhibits ‘therapeutic window’ phenomenon:
The therapeutic index of a drug is a measure of its:
Drug cumulation is the basis of organ toxicity of the following drug when used for prolonged periods:
A drug ‘R’ producing no response by itself causes the log dose-response curve of another drug ‘S’ to shift to the right in a parallel manner without decreasing the maximal response: Drug ‘R’ is a:
Compared to the drug named within parenthesis, which of the following drugs has a higher potency but lower efficacy:
Receptors perform the following function/functions:
