The following is not itself an efficacious diuretic, and is used only as an adjuvant/corrective to other diuretics:
Furosemide acts by inhibiting the following in the renal tubular cell:
Which of the following has a ‘self limiting diuretic’ (action of the drug itself causing changes which limit further diuresis) action:
The Na+-Cl– symport in the early distal convoluted tubule of the kidney is inhibited by:
At equinatriuretic doses which diuretic causes the maximum K+ loss:
Amiloride has the following effect on urinary cation excretion:
Select the diuretic that can cause gynaecomastia, hirsutism and menstrual disturbance as a side effect on long-term use:
The following diuretic abolishes the corticomedullary osmotic gradient in the kidney:
Choose the correct statement about osmotic diuretics:
The primary site of action of thiazide diuretics is:
The vasopressin action(s) mediated by V2 receptors include(s):
The current therapeutic indication of acetazolamide is:
Aldosterone increases Na+ reabsorption and K+ excretion in the renal collecting duct cells by:
Select the diuretic which is similar in efficacy and pattern of electrolyte excretion to furosemide, but is 40 times more potent dose to dose:
Use of potassium sparing diuretics in patients receiving the following drug needs close monitoring:
The following tissue is most sensitive to vasopressin:
Which of the following is a potassium retaining diuretic:
Thiazide diuretics and furosemide have directionally opposite effect on the net renal excretion of the following substance:
Individual drugs of thiazide and related class of diuretics differ markedly from each other in the following respect?
Choose the correct statement about amiloride
Parenteral furosemide is an alternative diuretic to mannitol in the following condition:
Which of the following peptides is a selective vasopressin V2 receptor agonist:
Long-term thiazide therapy can cause hyperglycaemia by:
Choose the correct statement about thiazide diuretics:
The most appropriate measure to overcome diminished responsiveness to furosemide after its long term use is:
